Biology Department

Professors: Robert S. Fritz (Chair), John H. Long, Jr., E. Pinina Norrod, Mark A. Schlessmanb, Kathleen M. Susman, Robert B. Suter; Associate Professors: Richard B. Hemmesab, David K. Jemiolo, Nancy Pokrywka, A. Marshall Pregnall, Margaret L. Ronsheim, J. William Straus; Assistant Professors:Cynthia K. Damer, Kam D. DahlquistbVisiting Assistant Professor: Jason Jones.

ab Absent on leave for the year.

a Absent on leave, first semester.

b Absent on leave, second semester.

Requirements for Concentration: 13 or 14 units: at the 100-level, Biology 105 and Biology 106 ; at the 200-level, 4 units of graded work, not including Biology 206 , with at least one course in each of the three areas described below; at the 300-level, 3 units of graded work; 4 or 5 units to be apportioned as follows:

a) 2 or 3 units in Chemistry: 108/109 or 125, and 244;

b) 2 units to be chosen from among Chemistry 245; Physics 113, 114; Mathematics 101, 102, 121, 122, or 125; Geology 151; Psychology 200; Neuroscience and Behavior 201; Environmental Science 281; and other intermediate or advanced science courses subject to departmental approval. One of the two units may also be an additional graded 200-level or 300-level Biology course (excluding 206) or ungraded independent research Biology 298 or 399.

200-level Subject Areas: Ecology, Evolution and Diversity, Biochemistry, Cellular and Molecular Biology, Developmental Biology and Physiology. 200-level course descriptions indicate which subject area each course fulfills. Students may also consult the Biology Department web pages, Biology Advisers, or the Chair.

Senior Year Requirements: 2 units of graded 300-level biology taken at Vassar College.

Independent Research: The biology department encourages students to engage in independent research with faculty mentors, and offers ungraded courses Biology 178 , 298, and 399. The department also offers Biology 303 , a graded research experience for senior majors. Students should consult the chair or individual faculty members for guidance in initiating independent research.

Field Work: The department offers field work in biology. Students should consult the field work office and a biology faculty adviser for details.

Teaching Certification: Students who wish to obtain secondary school teaching certification in biology should consult both the biology and education departments for appropriate course requirements.

Early Advising: Those students considering a concentration in biology, particularly those who have already identified an interest in a subdiscipline of biology, should consult a departmental adviser early in their freshman year to discuss appropriate course sequences. After declaration of the major, no NRO work is permissible in the major.

Postgraduate Work: Students considering graduate school or other professional schools should be aware that such schools usually require courses beyond the minimum biology major requirements. In general, students should have at least a full year of organic chemistry, a year of physics, and a year of calculus. Students are urged to begin their chemistry and other correlated sciences coursework as soon as possible, since this will assist them in successful completion of the biology major. Students should consult with the chair of biology or the pre-medical adviser at their earliest opportunity.

Further Information: For additional information on research opportunities, honors requirements, etc., please see the biology department.

Advisers: For the class of 2006, Mr. Jemiolo, Ms. Pokrywka; for the class of 2007 Mr. Long, Mr. Pregnall, Mr. Schlessman; for the class of 2008 Ms. Darner, Ms. Ronsheim, Ms. Susman.

Correlate Sequences in Biology:

The Department of Biology offers four correlate sequences, each with a different emphasis. Students interested in undertaking a correlate in biology should consult with one of the biology advisers assigned to each class (see above). The requirements for each are listed below:

Cellular Biology/Molecular Biology (6 or 7 units)

Biology 105 Introduction to Biological Processes (1)

Biology 106 Introduction to Biological Investigation (1)

Chemistry 108/109 or Chemistry 125

Two of the following:

Biology 202 Plant Physiology and Development (1)

Biology 205 Introduction to Microbiology (1)

Biology 228 Animal Physiology (1)

Biology 232 Developmental Biology (1)

Biology 238 Genetics (1)

Biology 272 Cellular Biochemistry (1)

One of the following:

Biology 316 Neurobiology (1)

Biology 323 Cell Biology (1)

Biology 324 Molecular Biology (1)

Biology 325 Bioinformation (1)

Biology 370 Immunology (1)

Animal Physiology (6 units)

Biology 105 Introduction to Biological Processes (1)

Biology 106 Introduction to Biological Investigation (1)

Biology 228 Animal Physiology (1)

Three of the following, at least one at the 300-level:

Biology 226 Animal Structure and Diversity (1)

Biology 232 Developmental Biology (1)

Biology 238 Genetics (1)

Biology 316 Neurobiology (1)

Biology 370 Immunology (1)

Ecology/Evolution (6 units)

Biology 105 Introduction to Biological Processes (1)

Biology 106 Introduction to Biological Investigation (1)

Biology 241 Ecology (1)

Biology 350 Evolutionary Biology (1)

One of the following:

Biology 202 Plant Physiology and Development (1)

Biology 205 Introduction to Microbiology (1)

Biology 238 Genetics (1)

One of the following:

Biology 208 Plant Structure and Diversity (1)

Biology 226 Animal Structure and Diversity (1)

Biology 352 Conservation Biology (1)

Biology 354 Plant-Animal Interactions (1)

Biology 356 Aquatic Ecology (1)

Behavior/Neurobiology (6 units)

Biology 105 Introduction to Biological Processes (1)

Biology 106 Introduction to Biological Investigation (1)

Two of the following:

Biology 226 Animal Structure and Diversity (1)

Biology 228 Animal Physiology (1)

Biology 241 Ecology (1)

One of the following:

Biology 232 Developmental Biology (1)

Biology 238 Genetics (1)

One of the following

Biology 316 Neurobiology (1)

Biology 340 Animal Behavior (1)

I. Introductory

105 a and b. Introduction to Biological Processes (1)

Development of critical thought, communication skills, and understanding of central concepts in biology, through exploration of a timely topic. The content of each section varies. The department.

106 a and b. Introduction to Biological Investigation (1)

Investigation of biological questions via extended laboratory or field projects. Emphasis is placed on observation skills, development and testing of hypotheses, experimental design, data collection, statistical analysis, and scientific writing and presentation. The department.

One 75 minute and one four hour period.

Biology 105 and 106 may be taken in any order. Students who have not taken any introductory biology should start with Biology 105 or Biology 106.

172 Microbial Wars (1)

(Same as Science, Society, and Technology 172) This course examines ways in which some microbes have beome a problem due to misuse by humans. The topics include resistance to antibiotics, emerging infections, and bioterrorism. Introductory material stresses the differences between microbes, including bacteria, protozoa, and viruses.

178 Special Projects in Biology (1⁄2)

Execution and analysis of a laboratory or field study. Project to be arranged with individual instructor. The department.

Open to freshmen and sophomores only.

II. Intermediate

Two units of 100-level biology taken at Vassar College are prerequisites for entry into 200-level courses unless otherwise stated.

202 Plant Physiology and Development (1)

An examination of the cellular and physiological bases of plant maintenance, growth, development, and reproduction; with emphasis on the values of different plants as experimental systems. Subject area: Developmental Biology and Physiology. Mr. Pregnall.

Three 50-minute periods; one 4-hour laboratory.

205 Introduction to Microbiology (1)

An introduction to the world of microbes, including bacteria, fungi, and viruses. The study of bacteria is stressed. Studies of the morphology, physiology, and genetics of bacteria are followed by their consideration in ecology, industry, and medicine. Subject area: Biochemistry, Cellular and Molecular Biology. Ms. Norrod.

Two 75-minute periods; two 2-hour laboratories.

[206. Environmental Biology] (1)

(Same as Science, Technology, and Society 206) A biological exploration of the impacts of contemporary agricultural production, transportation, waste disposal, and energy production, as well as human population growth, on the health of terrestrial and aquatic ecosystems. The course also examines biological conservation, genetically modified organisms, renewable resource utilization, and energy efficiency, and their roles in the transition to a sustainable society. Mr. Hemmes.

Prerequisite: Biology 151 or permission of instructor.

Not offered in 2005/06.

208 Plant Structure and Diversity (1)

A study of the origins and diversification of plants. Problems to be analyzed may include mechanical support, internal transport, mechanical and biochemical defenses, life-histories, reproductive strategies, and modes of speciation. Laboratories include comparative study of the divisions of plants and identification of locally common species and families in the field. Subject area: Ecology, Evolution, and Diversity. Mr. Pregnall, Ms. Ronsheim, or Mr. Schlessman.

Three 50-minute periods; one 4-hour laboratory.

226 Animal Structure and Diversity (1)

The structures and functions of animals are compared, analyzed, and interpreted in a phylogenetic context. Emphasis is placed on the unique innovations and common solutions evolved by different taxonomic groups to solve problems related to feeding, mobility, respiration, and reproduction. Laboratory work centers on the comparative study of the anatomy of species representative of the major animal phyla. Subject area: Ecology, Evolution, and Diversity. Mr. Long.

Three 50-minute periods; one 4-hour laboratory.

228 Animal Physiology (1)

A comparative examination of the approaches animals use to move, respire, eat, reproduce, sense, and regulate their internal environments. The physiological principles governing these processes are developed in lecture and applied in the laboratory. Subject area: Developmental Biology and Physiology. Mr. Long.

Recommended: Chemistry 108, 109, and Physics 113.

Three 50-minute periods; one 4-hour laboratory.

232 Developmental Biology (1)

The study of embryonic development including gametogenesis, fertilization, growth, and differentiation. Molecular concepts of gene regulation and cell interactions are emphasized. The laboratory emphasizes classical embryology and modern experimental techniques. Subject area: Developmental Biology and Physiology. Ms. Pokrywka or Mr. Straus.

Two 75-minute periods; one 4-hour laboratory.

238 Principles of Genetics (1)

Principles of genetics and methods of genetic analysis at the molecular, cellular, and organismal levels. Emphasis is placed on classical genetic experiments, as well as modern investigative techniques such as recombinant DNA technology, gene therapy, genetic testing, and the use of transgenic plants and animals. Laboratory work includes experiments on prokaryotes and eukaryotes. Subject area: Biochemistry, Cellular and Molecular Biology. Ms. Dahlquist, Ms. Damer, or Ms. Pokrywka.

Three 50-minute periods; one 4-hour laboratory.

241 Ecology (1)

Population growth, species interaction, and community patterns and processes of species or groups of species are discussed. The course emphasizes these interactions within the framework of evolutionary theory. Local habitats and organisms are used as examples of how organisms are distributed in space, how populations grow, why species are adapted to their habitats, how species interact, and how communities change. Field laboratories at Vassar Farm and other localities emphasize the formulation of answerable questions and methods to test hypotheses. Subject area: Ecology, Evolution, and Diversity. Mr. Fritz or Ms. Ronsheim.

Three 50-minute periods; one 4-hour field laboratory.

272 Biochemistry (1)

(Same as Chemistry 272) Basic course covering protein structure and synthesis, enzyme action, bio-energetic principles, electron transport and oxidative phosphorylation, selected metabolic pathways in prokaryotic and eukaryotic cells. Subject area: Biochemistry, Cellular and Molecular Biology. Mr. Jemiolo, Mr. Straus, or Mr. Eberhardt (Chemistry).

Prerequisite: Chemistry 244.

Three 50-minute periods; one 4-hour laboratory.

275 Paleontology (1)

(Same as Geology 275)

290 Field Work (1⁄2 or 1)

298 Independent Work (1⁄2 or 1)

Execution and analysis of a field, laboratory, or library study. The project, arranged with an individual instructor, is expected to have a substantial paper as its final product.

Permission of instructor is required.

III. Advanced

Two (2) units of 200-level biology are prerequisites for entry into 300-level courses; see each course for specific courses required or exceptions.

303 Senior Research (1)

Critical analysis, usually through observation or experimentation, of a specific research problem in biology. A student electing this course must first gain, by submission of a written research proposal, the support of a member of the biology faculty with whom to work out details of a research protocol. The formal research proposal, a final paper, and presentation of results are required parts of the course. A second faculty member participates both in the planning of the research and in final evaluation.

Permission of instructor is required.

316 Neurobiology (1)

An examination of nervous system function at the cellular level. The course emphasizes the physical and chemical foundations of intercellular communication, integration and processing of information, and principles of neural development. Laboratory includes demonstrations of biophysical methodology and experimental approaches to the study of nerve cells. Ms. Susman.

Prerequisites: 2 units of 200-level biology or 1 unit of 200-level biology and either Psychology 241 or Biopsychology 201. Recommended: Biology 228, 272.

323 Cell Biology (1)

Investigations with a biochemical emphasis into the dynamics of the eukaryotic cell. Topics include the cell cycle, membrane trafficking, cytoskeleton, and cell signaling. Ms. Damer or Ms. Pokrywka.

Prerequisite: Biology 272.

324 Molecular Biology (1)

(Same as Chemistry 324) An examination of the macromolecular processes underlying storage, transfer, and expression of genetic information. Topics include the structure, function, and synthesis of DNA; mutation and repair; the chemistry of RNA and protein synthesis; the regulation of gene expression; cancer and oncogenes; the molecular basis of cell differentiation; and genetic engineering. Mr. Jemiolo.

Prerequisites: one of the following: Biology 205, 238, or 272.

325 Bioinformatics (1)

Bioinformatics is the application of information technology (informatics) to biological data. Informatics is the representation, organization, manipulation, distribution, maintenance, and use of digital information. When applied to biological data, informatics provides databases and analytical tools for answering biological questions. Bioinformatics is inherently interdisciplinary, involving aspects of biology, computer science, mathematics, physics, and chemistry. While computers have been used to analyze biological data since their invention, the need for computational methods has recently exploded due to the huge amounts of data produced by genome sequencing projects and other high-throughput technologies. Bioinformatics techniques are being used to move the field of biology from a “one gene at a time” approach, to the analysis of whole systems. In this course, students learn current bioinformatics techniques to address systems-level biological questions. Topics include sequence alignment and phylogeny, biological databases, protein structure prediction, modeling pathways and networks, comparative genomics, and the analysis of high-throughput genomic and proteomic data. Ms. Dahlquist.

Prerequisite: Biology 238 or Biology / Chemistry 272.

One 4-hour computer laboratory.

340 Animal Behavior (1)

Examination of the relationship between behavior and the individual animal’s survival and reproductive success in its natural environment. Evolutionary, physiological, and developmental aspects of orientation, communication, habitat selection, foraging, reproductive tactics, and social behavior are considered. Methodology and experimental design is considered in lectures, but is given particular emphasis in the laboratory component of the course. Mr. Hemmes or Mr. Suter.

Prerequisites: 2 units of 200-level biology or 1 unit each of 200-level biology and psychology.

Recommended: Biology 226, 228, 238, or Psychology 200.

[350. Evolutionary Biology] (1)

Study of the history of evolutionary thought, mechanisms of evolutionary change, and controversies in the study of organic evolution. Topics include the origin and maintenance of genetic variability, natural selection, adaptation, origin of species, macroevolution, co-evolution, and human evolution.

Prerequisites: any two of Biology 208, 226, or 241; or permission of the instructor.

Not offered in 2005/06.

352 Conservation Biology (1)

(Same as Environmental Studies 352) Conservation Biology is a new science that has developed in response to the biological diversity crisis. The goals of conservation biology are to understand human impacts on biodiversity and to develop practical approaches for mitigating them. This course is designed to provide an up-to-date synthesis of the multiple disciplines of conservation biology, with particular emphasis on applied ecology and evolutionary biology. Topics may include kinds of biological diversity, genetics of small populations, population viability analysis, systematics and endangered species, pests and invasions, habitat fragmentation, reserve design, management plans for ecosystems and species, and restoration ecology. Ms. Ronsheim or Mr. Schlessman.

Prerequisites: 2 units of 200-level Biology, preferably from 206, 208, 238, or 241; or permission of the instructor.

[354. Plant-Animal Interactions] (1)

An examination of the predominant interactions between plants and animals that influence their ecology and evolution. The course focuses on the kinds of interactions (herbivory, mutualism, pollination, seed dispersal, etc.), the costs and benefits of interactions, the ecological contexts that favor certain types of species interactions (environmental stability, competition, and predation intensity), and the evolution (natural selection models and co-evolution) of interactions. Primary literature and case histories are regularly discussed and theories that explain the evolution and ecology of interactions are explored. The laboratory includes individual and group independent projects that permit observation and experimentation with plant-animal interactions. Mr. Fritz.

Prerequisite: Biology 241 or permission of instructor.

Not offered in 2005/06.

[356. Aquatic Ecology] (1)

A consideration of freshwater, estuarine, and marine habitats that examines material and energy fluxes through aquatic systems; physiological aspects of primary production; the biogeochemical cycling of nutrients; adaptations of organisms to physical and chemical aspects of aquatic environments; biological processes that structure selected communities; and the role of aquatic habitat in global change phenomena. Mr. Pregnall.

Not offered in 2005/06.

370 Immunology (1)

An examination of the immune response at the cellular and molecular levels. Topics include the structure, function, and synthesis of antibodies; transplantation and tumor immunology; immune tolerance; allergic responses; and immune deficiency diseases. Mechanisms for recognition; communication; and cooperation between different classes of lymphocytes in producing these various responses are stressed, as are the genetic basis of immunity and the cellular definition of “self’’ which makes each individual unique. Ms. Norrod.

Prerequisite: Chemistry 244 or permission of instructor; Biology 238, 272 recommended.

383 Topics in Vertebrate Paleontology (1)

(Same as Geology 383)

399 Senior Independent Work (1⁄2 or 1)

Execution and analysis of a field, laboratory, or library study. The project, to be arranged with an individual instructor, is expected to have a substantial paper as its final product.

Permission of instructor is required.

IV. Graduate

400 Thesis (1)

416 Neurobiology (1)

423 Cell Biology (1)

424 Molecular Biology (1)

440 Animal Behavior (1)

450 Evolutionary Biology (1)

454 Plant-Animal Interactions (1)

456 Aquatic Ecology (1)

470 Immunology (1)